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mitotane will reduce the extent or result of abemaciclib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of abemaciclib with sturdy CYP3A4 inducers lowers plasma concentration of abemaciclib and its metabolites.It's best to browse our information regarding abemaciclib with our common